The Ignatz Awards have a page up describing their sensible and quite-easy-to-follow submissions process. It involves sending six copies of a work that came out between June 1 and May 31 to one of the Big Planet stores -- it's a different one this time -- where they will be distributed to the secret panel of judges. You have until June 7 to get your stuff into their hands. That's become a very important award to that community for a lot of reasons, I think, but mostly that there's been something of a consistency in the kind of work submitted and honored and a corresponding consistency in that part of comics.
As always, I look forward to sitting in the audience and not knowing any of the presenters.