There's a ton of stuff in this article about the long history and I guess not-as-stellar recent story of Salon.com. One thing that I think binds comics to print publishing more generally is how modes of presentation and modes of structural organization have transformed two or three times and some businesses have ignored this entirely because that's what they are.
In other words, when you read the amounts of money involved in this article, you'll likely think: "Could I get to the end result of Salon with this amount of money?" The answer seems "Oh, sure." Other people have different expectations for what such an enterprise looks like and have a much more hesitant answer. The reality is always a bit more shaky than both.